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Identification of Grouped Rare and Common Variants via Penalized Logistic Regression

In spite of the success of genome-wide association studies in finding many common variants associated with disease, these variants seem to explain only a small proportion of the estimated heritability. Data collection has turned toward exome and whole genome sequencing, but it is well known that sin...

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Detalles Bibliográficos
Autores principales: Ayers, Kristin L, Cordell, Heather J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842118/
https://www.ncbi.nlm.nih.gov/pubmed/23836590
http://dx.doi.org/10.1002/gepi.21746