Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System

The discovery of the involvement of alpha-synuclein (α-syn) in Parkinson’s disease (PD) pathogenesis has resulted in the development and use of viral vector-mediated α-syn overexpression rodent models. The goal of these series of experiments was to characterize the neurodegeneration and functional d...

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Detalles Bibliográficos
Autores principales: Gombash, Sara E., Manfredsson, Fredric P., Kemp, Christopher J., Kuhn, Nathan C., Fleming, Sheila M., Egan, Ann E., Grant, Laura M., Ciucci, Michelle R., MacKeigan, Jeffrey P., Sortwell, Caryl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842242/
https://www.ncbi.nlm.nih.gov/pubmed/24312298
http://dx.doi.org/10.1371/journal.pone.0081426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842242/
https://www.ncbi.nlm.nih.gov/pubmed/24312298
http://dx.doi.org/10.1371/journal.pone.0081426

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