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Functional Characteristics of the Naked Mole Rat μ-Opioid Receptor
While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1) can underlie altered behavior...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842265/ https://www.ncbi.nlm.nih.gov/pubmed/24312175 http://dx.doi.org/10.1371/journal.pone.0079121 |