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Functional Characteristics of the Naked Mole Rat μ-Opioid Receptor
While humans and most animals respond to µ-opioid receptor (MOR) agonists with analgesia and decreased aggression, in the naked mole rat (NMR) opioids induce hyperalgesia and severe aggression. Single nucleotide polymorphisms in the human mu-opioid receptor gene (OPRM1) can underlie altered behavior...
Autores principales: | Busch-Dienstfertig, Melanie, Roth, Clarisse A., Stein, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842265/ https://www.ncbi.nlm.nih.gov/pubmed/24312175 http://dx.doi.org/10.1371/journal.pone.0079121 |
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