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Reverse Engineering the Cooperative Machinery of Human Hemoglobin
Hemoglobin transports molecular oxygen from the lungs to all human tissues for cellular respiration. Its α(2)β(2) tetrameric assembly undergoes cooperative binding and releasing of oxygen for superior efficiency and responsiveness. Over past decades, hundreds of hemoglobin structures were determined...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842276/ https://www.ncbi.nlm.nih.gov/pubmed/24312167 http://dx.doi.org/10.1371/journal.pone.0077363 |