Cargando…

Dynamic Impacts of the Inhibition of the Molecular Chaperone Hsp90 on the T-Cell Proteome Have Implications for Anti-Cancer Therapy

The molecular chaperone Hsp90-dependent proteome represents a complex protein network of critical biological and medical relevance. Known to associate with proteins with a broad variety of functions termed clients, Hsp90 maintains key essential and oncogenic signalling pathways. Consequently, Hsp90...

Descripción completa

Detalles Bibliográficos
Autores principales: Fierro-Monti, Ivo, Echeverria, Pablo, Racle, Julien, Hernandez, Celine, Picard, Didier, Quadroni, Manfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842317/
https://www.ncbi.nlm.nih.gov/pubmed/24312219
http://dx.doi.org/10.1371/journal.pone.0080425