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Positive Evolutionary Selection On the RIG-I-Like Receptor Genes in Mammals
The mammalian RIG-I-like receptors, RIG-I, MDA5 and LGP2, are a family of DExD/H box RNA helicases responsible for the cytoplasmic detection of viral RNA. These receptors detect a variety of RNA viruses, or DNA viruses that express unusual RNA species, many of which are responsible for a great numbe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842351/ https://www.ncbi.nlm.nih.gov/pubmed/24312370 http://dx.doi.org/10.1371/journal.pone.0081864 |