Positive Evolutionary Selection On the RIG-I-Like Receptor Genes in Mammals

The mammalian RIG-I-like receptors, RIG-I, MDA5 and LGP2, are a family of DExD/H box RNA helicases responsible for the cytoplasmic detection of viral RNA. These receptors detect a variety of RNA viruses, or DNA viruses that express unusual RNA species, many of which are responsible for a great numbe...

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Detalles Bibliográficos
Autores principales: Lemos de Matos, Ana, McFadden, Grant, Esteves, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842351/
https://www.ncbi.nlm.nih.gov/pubmed/24312370
http://dx.doi.org/10.1371/journal.pone.0081864

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