Attenuated Expression of Apoptosis Stimulating Protein of p53-2 (ASPP2) in Human Acute Leukemia Is Associated with Therapy Failure

Inactivation of the p53 pathway is a universal event in human cancers and promotes tumorigenesis and resistance to chemotherapy. Inactivating p53 mutations are uncommon in non-complex karyotype leukemias, thus the p53-pathway must be inactivated by other mechanisms. The Apoptosis Stimulating Protein...

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Detalles Bibliográficos
Autores principales: Schittenhelm, Marcus M., Illing, Barbara, Ahmut, Figen, Rasp, Katharina Henriette, Blumenstock, Gunnar, Döhner, Konstanze, Lopez, Charles D., Kampa-Schittenhelm, Kerstin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842400/
https://www.ncbi.nlm.nih.gov/pubmed/24312201
http://dx.doi.org/10.1371/journal.pone.0080193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842400/
https://www.ncbi.nlm.nih.gov/pubmed/24312201
http://dx.doi.org/10.1371/journal.pone.0080193

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