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Mammalian Mon2/Ysl2 regulates endosome-to-Golgi trafficking but possesses no guanine nucleotide exchange activity toward Arl1 GTPase

Arl1 is a member of Arf family small GTPases that is essential for the organization and function of Golgi complex. Mon2/Ysl2, which shares significant homology with Sec7 family Arf guanine nucleotide exchange factors, was poorly characterized in mammalian cells. Here, we report the first in depth ch...

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Detalles Bibliográficos
Autores principales: Mahajan, Divyanshu, Boh, Boon Kim, Zhou, Yan, Chen, Li, Cornvik, Tobias Carl, Hong, Wanjin, Lu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842536/
https://www.ncbi.nlm.nih.gov/pubmed/24285343
http://dx.doi.org/10.1038/srep03362