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Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn’s disease/infectious colitis and healthy controls

BACKGROUND: Inhibition of prolyl hydroxylases (PHDs) leads to the induction of a transcriptional program that, in the gut, promotes intestinal epithelial cell survival. PHD inhibitors have recently been suggested as a promising alternative treatment for inflammatory bowel disease (IBD). In this stud...

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Detalles Bibliográficos
Autores principales: Van Welden, Sophie, Laukens, Debby, Ferdinande, Liesbeth, De Vos, Martine, Hindryckx, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842628/
https://www.ncbi.nlm.nih.gov/pubmed/24257430
http://dx.doi.org/10.1186/1476-9255-10-36