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Ets-1 regulates intracellular glutathione levels: key target for resistant ovarian cancer

BACKGROUND: Ovarian cancer is characterized by high rates of metastasis and therapeutic resistance. Many chemotherapeutic agents rely on the induction of oxidative stress to cause cancer cell death, thus targeting redox regulation is a promising strategy to overcome drug resistance. METHODS: We have...

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Detalles Bibliográficos
Autores principales: Verschoor, Meghan L, Singh, Gurmit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842663/
https://www.ncbi.nlm.nih.gov/pubmed/24238102
http://dx.doi.org/10.1186/1476-4598-12-138