Methods and challenges in timing chromosomal abnormalities within cancer samples

Motivation: Tumors acquire many chromosomal amplifications, and those acquired early in the lifespan of the tumor may be not only important for tumor growth but also can be used for diagnostic purposes. Many methods infer the order of the accumulation of abnormalities based on their occurrence in a...

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Detalles Bibliográficos
Autores principales: Purdom, Elizabeth, Ho, Christine, Grasso, Catherine S., Quist, Michael J., Cho, Raymond J., Spellman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842754/
https://www.ncbi.nlm.nih.gov/pubmed/24064421
http://dx.doi.org/10.1093/bioinformatics/btt546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842754/
https://www.ncbi.nlm.nih.gov/pubmed/24064421
http://dx.doi.org/10.1093/bioinformatics/btt546

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