QSSPN: dynamic simulation of molecular interaction networks describing gene regulation, signalling and whole-cell metabolism in human cells

Motivation: Dynamic simulation of genome-scale molecular interaction networks will enable the mechanistic prediction of genotype–phenotype relationships. Despite advances in quantitative biology, full parameterization of whole-cell models is not yet possible. Simulation methods capable of using avai...

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Detalles Bibliográficos
Autores principales: Fisher, Ciarán P., Plant, Nicholas J., Moore, J. Bernadette, Kierzek, Andrzej M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842758/
https://www.ncbi.nlm.nih.gov/pubmed/24064420
http://dx.doi.org/10.1093/bioinformatics/btt552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842758/
https://www.ncbi.nlm.nih.gov/pubmed/24064420
http://dx.doi.org/10.1093/bioinformatics/btt552

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