VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets

Platelets were activated under the infection with H. pylori in human and mice. We investigated the role of VacA, an exotoxin released by H. pylori in this context. Acid-activated VacA, but not heated VacA, induced platelet CD62P expression. However, VacA reacted with none of the alleged VacA recepto...

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Detalles Bibliográficos
Autores principales: Satoh, Kaneo, Hirayama, Toshiya, Takano, Katsuhiro, Suzuki-Inoue, Katsue, Sato, Tadashi, Ohta, Masato, Nakagomi, Junko, Ozaki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842841/
https://www.ncbi.nlm.nih.gov/pubmed/24219705
http://dx.doi.org/10.1186/1477-9560-11-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842841/
https://www.ncbi.nlm.nih.gov/pubmed/24219705
http://dx.doi.org/10.1186/1477-9560-11-23

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