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Large-Scale Analysis of Peptide Sequence Variants: The Case for High-Field Asymmetric Waveform Ion Mobility Spectrometry

[Image: see text] Large scale analysis of proteins by mass spectrometry is becoming increasingly routine; however, the presence of peptide isomers remains a significant challenge for both identification and quantitation in proteomics. Classes of isomers include sequence inversions, structural isomer...

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Detalles Bibliográficos
Autores principales: Creese, Andrew J., Smart, Jade, Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842852/
https://www.ncbi.nlm.nih.gov/pubmed/23646896
http://dx.doi.org/10.1021/ac400646m