Long exposure to mature ooplasm can alter DNA methylation at imprinted loci in non-growing oocytes but not in prospermatogonia

DNA methylation imprints that are established in spermatogenesis and oogenesis are essential for functional gametes. However, the mechanisms underlying gamete-specific imprinting remain unclear. In this study, we investigated whether male and female gametes derived from newborn mice are epigenetical...

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Detalles Bibliográficos
Autores principales: Obata, Yayoi, Wakai, Takuya, Hara, Satoshi, Kono, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2014
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842912/
https://www.ncbi.nlm.nih.gov/pubmed/24123131
http://dx.doi.org/10.1530/REP-13-0359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842912/
https://www.ncbi.nlm.nih.gov/pubmed/24123131
http://dx.doi.org/10.1530/REP-13-0359

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