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Meleagrin, a New FabI Inhibitor from Penicillium chryosogenum with at Least One Additional Mode of Action

Bacterial enoyl-acyl carrier protein reductase (FabI) is a promising novel antibacterial target. We isolated a new class of FabI inhibitor from Penicillium chrysogenum, which produces various antibiotics, the mechanisms of some of them are unknown. The isolated FabI inhibitor was determined to be me...

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Detalles Bibliográficos
Autores principales: Zheng, Chang Ji, Sohn, Mi-Jin, Lee, Sangku, Kim, Won-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842914/
https://www.ncbi.nlm.nih.gov/pubmed/24312171
http://dx.doi.org/10.1371/journal.pone.0078922