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Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain

Early Alzheimer's disease (AD) is characterized by memory loss and hippocampal atrophy with relative sparing of basal ganglia. Activation of glutamate NMDA receptors in the hippocampus is an important step in memory formation. We measured the density of NMDA receptors in samples of hippocampus,...

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Detalles Bibliográficos
Autores principales: Kravitz, Efrat, Gaisler-Salomon, Inna, Biegon, Anat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842934/
https://www.ncbi.nlm.nih.gov/pubmed/24312282
http://dx.doi.org/10.1371/journal.pone.0081244