NEDD4L Is Downregulated in Colorectal Cancer and Inhibits Canonical WNT Signaling

The NEDD4 family of E3 ubiquitin ligases includes nine members. Each is a modular protein, containing an N-terminal C2 domain for cell localization, two-to-four central WW domains for substrate recognition, and a C-terminal, catalytic HECT domain, which is responsible for catalyzing the ubiquitylati...

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Detalles Bibliográficos
Autores principales: Tanksley, Jarred P., Chen, Xi, Coffey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842946/
https://www.ncbi.nlm.nih.gov/pubmed/24312311
http://dx.doi.org/10.1371/journal.pone.0081514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842946/
https://www.ncbi.nlm.nih.gov/pubmed/24312311
http://dx.doi.org/10.1371/journal.pone.0081514

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