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Identification of miR-30e* Regulation of Bmi1 Expression Mediated by Tumor-Associated Macrophages in Gastrointestinal Cancer

Bmi1 is overexpressed in a variety of human cancers including gastrointestinal cancer. The high expression level of Bmi1 protein is associated with poor prognosis of gastrointestinal cancer patients. On the other hand, tumor-associated macrophages (TAMs) contribute to tumor growth, invasion, and met...

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Detalles Bibliográficos
Autores principales: Sugihara, Hidetaka, Ishimoto, Takatsugu, Watanabe, Masayuki, Sawayama, Hiroshi, Iwatsuki, Masaaki, Baba, Yoshifumi, Komohara, Yoshihiro, Takeya, Motohiro, Baba, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842972/
https://www.ncbi.nlm.nih.gov/pubmed/24312366
http://dx.doi.org/10.1371/journal.pone.0081839