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Functional overlap among distinct G1/S inhibitory pathways allows robust G1 arrest by yeast mating pheromones

In budding yeast, mating pheromones arrest the cell cycle in G1 phase via a pheromone-activated Cdk-inhibitor (CKI) protein, Far1. Alternate pathways must also exist, however, because deleting the cyclin CLN2 restores pheromone arrest to far1∆ cells. Here we probe whether these alternate pathways re...

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Detalles Bibliográficos
Autores principales: Pope, Patricia A., Pryciak, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842994/
https://www.ncbi.nlm.nih.gov/pubmed/24088572
http://dx.doi.org/10.1091/mbc.E13-07-0373