Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity

Natural killer (NK) lymphocytes contain lysosome-related organelles (LROs), known as lytic granules, which upon formation of immune synapse with the target cell, polarize toward the immune synapse to deliver their contents to the target cell membrane. Here, we identify a small GTP-binding protein, A...

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Detalles Bibliográficos
Autores principales: Tuli, Amit, Thiery, Jerome, James, Ashley M., Michelet, Xavier, Sharma, Mahak, Garg, Salil, Sanborn, Keri B., Orange, Jordan S., Lieberman, Judy, Brenner, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842998/
https://www.ncbi.nlm.nih.gov/pubmed/24088571
http://dx.doi.org/10.1091/mbc.E13-05-0259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842998/
https://www.ncbi.nlm.nih.gov/pubmed/24088571
http://dx.doi.org/10.1091/mbc.E13-05-0259

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