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Accelerated growth in the absence of DNA replication origins

DNA replication initiates at defined sites called origins, which serve as binding sites for initiator proteins that recruit the replicative machinery. Origins differ in number and structure across the three domains of life(1) and their properties determine the dynamics of chromosome replication. Bac...

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Detalles Bibliográficos
Autores principales: Hawkins, Michelle, Malla, Sunir, Blythe, Martin J., Nieduszynski, Conrad A., Allers, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843117/
https://www.ncbi.nlm.nih.gov/pubmed/24185008
http://dx.doi.org/10.1038/nature12650