Characterisation of Weibel–Palade body fusion by amperometry in endothelial cells reveals fusion pore dynamics and the effect of cholesterol on exocytosis

Regulated secretion from endothelial cells is mediated by Weibel–Palade body (WPB) exocytosis. Plasma membrane cholesterol is implicated in regulating secretory granule exocytosis and fusion pore dynamics; however, its role in modulating WPB exocytosis is not clear. To address this we combined high-...

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Detalles Bibliográficos
Autores principales: Cookson, Emma A., Conte, Ianina L., Dempster, John, Hannah, Matthew J., Carter, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843139/
https://www.ncbi.nlm.nih.gov/pubmed/24127569
http://dx.doi.org/10.1242/jcs.138438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843139/
https://www.ncbi.nlm.nih.gov/pubmed/24127569
http://dx.doi.org/10.1242/jcs.138438

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