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Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity

Transcription activator-like effector (TALE) nuclease (TALEN) is a site-specific nuclease, which can be freely designed and easily constructed. Numerous methods of constructing TALENs harboring different TALE scaffolds and repeat variants have recently been reported. However, the functionalities of...

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Detalles Bibliográficos
Autores principales: Sakuma, Tetsushi, Ochiai, Hiroshi, Kaneko, Takehito, Mashimo, Tomoji, Tokumasu, Daisuke, Sakane, Yuto, Suzuki, Ken-ichi, Miyamoto, Tatsuo, Sakamoto, Naoaki, Matsuura, Shinya, Yamamoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843162/
https://www.ncbi.nlm.nih.gov/pubmed/24287550
http://dx.doi.org/10.1038/srep03379