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Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity
Transcription activator-like effector (TALE) nuclease (TALEN) is a site-specific nuclease, which can be freely designed and easily constructed. Numerous methods of constructing TALENs harboring different TALE scaffolds and repeat variants have recently been reported. However, the functionalities of...
Autores principales: | Sakuma, Tetsushi, Ochiai, Hiroshi, Kaneko, Takehito, Mashimo, Tomoji, Tokumasu, Daisuke, Sakane, Yuto, Suzuki, Ken-ichi, Miyamoto, Tatsuo, Sakamoto, Naoaki, Matsuura, Shinya, Yamamoto, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843162/ https://www.ncbi.nlm.nih.gov/pubmed/24287550 http://dx.doi.org/10.1038/srep03379 |
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