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Development of novel DNA vaccine for VEGF in murine cancer model

We developed DNA vaccine for vascular endothelial growth factor (VEGF), which may provide the therapeutic option instead of anti-VEGF antibody, bevacizumab. Plasmid containing VEGF mini-gene was constructed in the insertion of B-cell epitope of Hepatitis B core protein [HBc-VEGF], which was an epito...

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Detalles Bibliográficos
Autores principales: Kyutoku, Mariko, Nakagami, Hironori, Koriyama, Hiroshi, Tomioka, Hideki, Nakagami, Futoshi, Shimamura, Munehisa, Kurinami, Hitomi, Zhengda, Pang, Jo, Dong Hyun, Kim, Jeong Hun, Takakura, Nobuyuki, Morishita, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843165/
https://www.ncbi.nlm.nih.gov/pubmed/24287585
http://dx.doi.org/10.1038/srep03380