Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation

BACKGROUND: The Blood–brain barrier (BBB) controls brain supply with oxygen and nutrients, and protects the brain from toxic metabolites, such as beta-amyloid (Aβ) peptides. The neurovascular unit (NVU) couples vascular and neuronal functions by controlling BBB parameters based on brain needs. As su...

Descripción completa

Detalles Bibliográficos
Autores principales: ElAli, Ayman, Thériault, Peter, Préfontaine, Paul, Rivest, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843528/
https://www.ncbi.nlm.nih.gov/pubmed/24252187
http://dx.doi.org/10.1186/2051-5960-1-75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843528/
https://www.ncbi.nlm.nih.gov/pubmed/24252187
http://dx.doi.org/10.1186/2051-5960-1-75

Ejemplares similares