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Impact of HIV-1 Backbone on Neutralization Sensitivity: Neutralization Profiles of Heterologous Envelope Glycoproteins Expressed in Native Subtype C and CRF01_AE Backbone

Standardized assays to assess vaccine and antiviral drug efficacy are critical for the development of protective HIV-1 vaccines and drugs. These immune assays will be advanced by the development of standardized viral stocks, such as HIV-1 infectious molecular clones (IMC), that i) express a reporter...

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Detalles Bibliográficos
Autores principales: Chenine, Agnès-Laurence, Wieczorek, Lindsay, Sanders-Buell, Eric, Wesberry, Maggie, Towle, Teresa, Pillis, Devin M., Molnar, Sebastian, McLinden, Robert, Edmonds, Tara, Hirsch, Ivan, O’Connell, Robert, McCutchan, Francine E., Montefiori, David C., Ochsenbauer, Christina, Kappes, John C., Kim, Jerome H., Polonis, Victoria R., Tovanabutra, Sodsai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843658/
https://www.ncbi.nlm.nih.gov/pubmed/24312165
http://dx.doi.org/10.1371/journal.pone.0076104