Resistance to Degradation and Cellular Distribution are Important Features for the Antitumor Activity of Gomesin

Many reports have shown that antimicrobial peptides exhibit anticancer abilities. Gomesin (Gm) exhibits potent cytotoxic activity against cancer cells by a membrane pore formation induced after well-orchestrated intracellular mechanisms. In this report, the replacements of the Cys by Ser or Thr, and...

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Detalles Bibliográficos
Autores principales: Buri, Marcus V., Domingues, Tatiana M., Paredes-Gamero, Edgar J., Casaes-Rodrigues, Rafael L., Rodrigues, Elaine Guadelupe, Miranda, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843672/
https://www.ncbi.nlm.nih.gov/pubmed/24312251
http://dx.doi.org/10.1371/journal.pone.0080924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843672/
https://www.ncbi.nlm.nih.gov/pubmed/24312251
http://dx.doi.org/10.1371/journal.pone.0080924

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