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Resistance to Degradation and Cellular Distribution are Important Features for the Antitumor Activity of Gomesin
Many reports have shown that antimicrobial peptides exhibit anticancer abilities. Gomesin (Gm) exhibits potent cytotoxic activity against cancer cells by a membrane pore formation induced after well-orchestrated intracellular mechanisms. In this report, the replacements of the Cys by Ser or Thr, and...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843672/ https://www.ncbi.nlm.nih.gov/pubmed/24312251 http://dx.doi.org/10.1371/journal.pone.0080924 |