Down-Regulation of miR-126 Is Associated with Colorectal Cancer Cells Proliferation, Migration and Invasion by Targeting IRS-1 via the AKT and ERK1/2 Signaling Pathways

BACKGROUND: Colorectal carcinoma (CRC) is one of the leading causes of cancer-related mortality worldwide. MicroRNAs (miRNAs, miRs) play important roles in carcinogenesis. MiR-126 has been shown to be down-regulated in CRC. In this study, we identified the potential effects of miR-126 on some import...

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Detalles Bibliográficos
Autores principales: Zhou, Yu, Feng, Xiao, Liu, Ya-ling, Ye, Shi-cai, Wang, Hao, Tan, Wen-kai, Tian, Ting, Qiu, Yu-mei, Luo, He-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843680/
https://www.ncbi.nlm.nih.gov/pubmed/24312276
http://dx.doi.org/10.1371/journal.pone.0081203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843680/
https://www.ncbi.nlm.nih.gov/pubmed/24312276
http://dx.doi.org/10.1371/journal.pone.0081203

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