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Inhibition of Protein Kinase C Delta Attenuates Allergic Airway Inflammation through Suppression of PI3K/Akt/mTOR/HIF-1 Alpha/VEGF Pathway

Vascular endothelial growth factor (VEGF) is supposed to contribute to the pathogenesis of allergic airway disease. VEGF expression is regulated by a variety of stimuli such as nitric oxide, growth factors, and hypoxia-inducible factor-1 alpha (HIF-1α). Recently, inhibition of the mammalian target o...

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Detalles Bibliográficos
Autores principales: Choi, Yun Ho, Jin, Guang Yu, Li, Liang chang, Yan, Guang Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843701/
https://www.ncbi.nlm.nih.gov/pubmed/24312355
http://dx.doi.org/10.1371/journal.pone.0081773