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α-Synuclein Oligomers Induced by Docosahexaenoic Acid Affect Membrane Integrity

A key feature of Parkinson disease is the aggregation of α-synuclein and its intracellular deposition in fibrillar form. Increasing evidence suggests that the pathogenicity of α-synuclein is correlated with the activity of oligomers formed in the early stages of its aggregation process. Oligomers to...

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Detalles Bibliográficos
Autores principales: Fecchio, Chiara, De Franceschi, Giorgia, Relini, Annalisa, Greggio, Elisa, Dalla Serra, Mauro, Bubacco, Luigi, Polverino de Laureto, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843715/
https://www.ncbi.nlm.nih.gov/pubmed/24312431
http://dx.doi.org/10.1371/journal.pone.0082732