Smooth Muscle LDL Receptor-Related Protein-1 Deletion Induces Aortic Insufficiency and Promotes Vascular Cardiomyopathy in Mice

Valvular disease is common in patients with Marfan syndrome and can lead to cardiomyopathy. However, some patients develop cardiomyopathy in the absence of hemodynamically significant valve dysfunction, suggesting alternative mechanisms of disease progression. Disruption of LDL receptor-related prot...

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Detalles Bibliográficos
Autores principales: Basford, Joshua E., Koch, Sheryl, Anjak, Ahmad, Singh, Vivek P., Krause, Eric G., Robbins, Nathan, Weintraub, Neal L., Hui, David Y., Rubinstein, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843717/
https://www.ncbi.nlm.nih.gov/pubmed/24312398
http://dx.doi.org/10.1371/journal.pone.0082026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843717/
https://www.ncbi.nlm.nih.gov/pubmed/24312398
http://dx.doi.org/10.1371/journal.pone.0082026

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