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Smooth Muscle LDL Receptor-Related Protein-1 Deletion Induces Aortic Insufficiency and Promotes Vascular Cardiomyopathy in Mice
Valvular disease is common in patients with Marfan syndrome and can lead to cardiomyopathy. However, some patients develop cardiomyopathy in the absence of hemodynamically significant valve dysfunction, suggesting alternative mechanisms of disease progression. Disruption of LDL receptor-related prot...
Autores principales: | Basford, Joshua E., Koch, Sheryl, Anjak, Ahmad, Singh, Vivek P., Krause, Eric G., Robbins, Nathan, Weintraub, Neal L., Hui, David Y., Rubinstein, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843717/ https://www.ncbi.nlm.nih.gov/pubmed/24312398 http://dx.doi.org/10.1371/journal.pone.0082026 |
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