The MEK-ERK Pathway Is Necessary for Serine Phosphorylation of Mitochondrial STAT3 and Ras-Mediated Transformation

Activating mutations in the RasGTPases are the most common oncogenic lesions in human cancer. Similarly, elevated STAT3 expression and/or phosphorylation are observed in the majority of human cancers. We recently found that activated Ras requires a mitochondrial rather than a nuclear activity of STA...

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Detalles Bibliográficos
Autores principales: Gough, Daniel J., Koetz, Lisa, Levy, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843736/
https://www.ncbi.nlm.nih.gov/pubmed/24312439
http://dx.doi.org/10.1371/journal.pone.0083395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843736/
https://www.ncbi.nlm.nih.gov/pubmed/24312439
http://dx.doi.org/10.1371/journal.pone.0083395

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