Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media

Chronic otitis media (OM) is common in Down syndrome (DS), but underlying aetiology is unclear. We analysed the entire available mouse resource of partial trisomy models of DS looking for histological evidence of chronic middle-ear inflammation. We found a highly penetrant OM in the Dp(16)1Yey mouse...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhutta, Mahmood F., Cheeseman, Michael T., Herault, Yann, Yu, Yuejin E., Brown, Steve D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843744/
https://www.ncbi.nlm.nih.gov/pubmed/24068166
http://dx.doi.org/10.1007/s00335-013-9475-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843744/
https://www.ncbi.nlm.nih.gov/pubmed/24068166
http://dx.doi.org/10.1007/s00335-013-9475-x

Ejemplares similares