Insight into the HIV-1 Vif SOCS-box–ElonginBC interaction

The HIV-1 viral infectivity factor (Vif) neutralizes cell-encoded antiviral APOBEC3 proteins by recruiting a cellular ElonginB (EloB)/ElonginC (EloC)/Cullin5-containing ubiquitin ligase complex, resulting in APOBEC3 ubiquitination and proteolysis. The suppressors-of-cytokine-signalling-like domain (...

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Detalles Bibliográficos
Autores principales: Lu, Zhisheng, Bergeron, Julien R. C., Atkinson, R. Andrew, Schaller, Torsten, Veselkov, Dennis A., Oregioni, Alain, Yang, Yi, Matthews, Stephen J., Malim, Michael H., Sanderson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843819/
https://www.ncbi.nlm.nih.gov/pubmed/24225024
http://dx.doi.org/10.1098/rsob.130100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843819/
https://www.ncbi.nlm.nih.gov/pubmed/24225024
http://dx.doi.org/10.1098/rsob.130100

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