Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis

Histone deacetylases (HDAC) are present in the epidermal layer of the skin, outer root sheath and hair matrix. To investigate how histone acetylation affects skin morphogenesis and homeostasis, mice were generated with a K14 promoter-mediated reduction of Hdac1 or Hdac2. The skin of HDAC1 null (K14-...

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Detalles Bibliográficos
Autores principales: Hughes, Michael W., Jiang, Ting-Xin, Lin, Sung-Jan, Leung, Yvonne, Kobielak, Krzysztof, Widelitz, Randall B., Chuong, Cheng Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843967/
https://www.ncbi.nlm.nih.gov/pubmed/23792463
http://dx.doi.org/10.1038/jid.2013.283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843967/
https://www.ncbi.nlm.nih.gov/pubmed/23792463
http://dx.doi.org/10.1038/jid.2013.283

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