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Adventitial transduction of lentivirus-shRNA-VEGF-A in arteriovenous fistula reduces venous stenosis formation

Venous neointimal hyperplasia (VNH) causes hemodialysis vascular access failure. Here we tested whether VNH formation occurs in part due to local vessel hypoxia caused by surgical trauma to the vasa vasorum of the outflow vein at the time of arteriovenous fistula placement. Selective targeting of th...

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Detalles Bibliográficos
Autores principales: Yang, Binxia, Janardhanan, Rajiv, Vohra, Pawan, Greene, Eddie L, Bhattacharya, Santanu, Withers, Sarah, Roy, Bhaskar, Nieves Torres, Evelyn C, Mandrekar, Jaywant, Leof, Edward B, Mukhopadhyay, Debabrata, Misra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844094/
https://www.ncbi.nlm.nih.gov/pubmed/23924957
http://dx.doi.org/10.1038/ki.2013.290