Cargando…

Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

AIMS: Aldosterone plays a crucial role in cardiovascular disease. ‘Systemic’ inhibition of its mineralocorticoid receptor (MR) decreases atherosclerosis by reducing inflammation and oxidative stress. Obesity, an important cardiovascular risk factor, is an inflammatory disease associated with increas...

Descripción completa

Detalles Bibliográficos
Autores principales: Schäfer, Nicola, Lohmann, Christine, Winnik, Stephan, van Tits, Lambertus J., Miranda, Melroy X., Vergopoulos, Athanasios, Ruschitzka, Frank, Nussberger, Jürg, Berger, Stefan, Lüscher, Thomas F., Verrey, François, Matter, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844149/
https://www.ncbi.nlm.nih.gov/pubmed/23594590
http://dx.doi.org/10.1093/eurheartj/eht095