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Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity
AIMS: Aldosterone plays a crucial role in cardiovascular disease. ‘Systemic’ inhibition of its mineralocorticoid receptor (MR) decreases atherosclerosis by reducing inflammation and oxidative stress. Obesity, an important cardiovascular risk factor, is an inflammatory disease associated with increas...
Autores principales: | Schäfer, Nicola, Lohmann, Christine, Winnik, Stephan, van Tits, Lambertus J., Miranda, Melroy X., Vergopoulos, Athanasios, Ruschitzka, Frank, Nussberger, Jürg, Berger, Stefan, Lüscher, Thomas F., Verrey, François, Matter, Christian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844149/ https://www.ncbi.nlm.nih.gov/pubmed/23594590 http://dx.doi.org/10.1093/eurheartj/eht095 |
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