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Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells

The retina is constantly subjected to oxidative stress, which is countered by potent antioxidative systems present in retinal pigment epithelial (RPE) cells. Disruption of these systems leads to the development of age-related macular degeneration. Thioredoxin 2 (Trx2) is a potent antioxidant, which...

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Detalles Bibliográficos
Autores principales: Sugano, Eriko, Murayama, Namie, Takahashi, Maki, Tabata, Kitako, Tamai, Makoto, Tomita, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844160/
https://www.ncbi.nlm.nih.gov/pubmed/24319591
http://dx.doi.org/10.1155/2013/185825