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Efficient Haplotype Block Partitioning and Tag SNP Selection Algorithms under Various Constraints

Patterns of linkage disequilibrium plays a central role in genome-wide association studies aimed at identifying genetic variation responsible for common human diseases. These patterns in human chromosomes show a block-like structure, and regions of high linkage disequilibrium are called haplotype bl...

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Detalles Bibliográficos
Autores principales: Chen, Wen-Pei, Hung, Che-Lun, Lin, Yaw-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844216/
https://www.ncbi.nlm.nih.gov/pubmed/24319694
http://dx.doi.org/10.1155/2013/984014