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Efficient Haplotype Block Partitioning and Tag SNP Selection Algorithms under Various Constraints
Patterns of linkage disequilibrium plays a central role in genome-wide association studies aimed at identifying genetic variation responsible for common human diseases. These patterns in human chromosomes show a block-like structure, and regions of high linkage disequilibrium are called haplotype bl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844216/ https://www.ncbi.nlm.nih.gov/pubmed/24319694 http://dx.doi.org/10.1155/2013/984014 |