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Association analysis of complex diseases using triads, parent-child dyads and singleton monads

BACKGROUND: Triad families are routinely used to test association between genetic variants and complex diseases. Triad studies are important and popular since they are robust in terms of being less prone to false positives due to population structure. In practice, one may collect not only complete t...

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Detalles Bibliográficos
Autores principales: Fan, Ruzong, Lee, Annie, Lu, Zhaohui, Liu, Aiyi, Troendle, James F, Mills, James L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844511/
https://www.ncbi.nlm.nih.gov/pubmed/24007308
http://dx.doi.org/10.1186/1471-2156-14-78