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Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D(3)-MARRS
We previously reported that diosgenin, a plant-derived steroidal sapogenin, improved memory and reduced axonal degeneration in an Alzheimer's disease mouse model. Diosgenin directly activated the membrane-associated rapid response steroid-binding receptor (1,25D(3)-MARRS) in neurons. However, 1...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844946/ https://www.ncbi.nlm.nih.gov/pubmed/24292207 http://dx.doi.org/10.1038/srep03395 |