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Sodium Valproate Inhibits the Growth of Human Cholangiocarcinoma In Vitro and In Vivo

Background. None of treatment options for Cholangiocarcinoma (CCA), including surgery, adjuvant radiotherapy and chemotherapy, and ultimately liver transplantation, have been shown to substantially improve the survival rate in patients with CCA. Valproic acid (VPA), a histone deacetylase inhibitor,...

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Detalles Bibliográficos
Autores principales: Wang, Bing, Yang, Rui, Wu, Yue, Li, Hongbo, Hu, Zouxiao, Chen, Yongjun, Zou, Shengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845332/
https://www.ncbi.nlm.nih.gov/pubmed/24324485
http://dx.doi.org/10.1155/2013/374593