ER Dysfunction and Protein Folding Stress in ALS

Amyotrophic lateral sclerosis (ALS) is the most frequent paralytic disease in adults. Most ALS cases are considered sporadic with no clear genetic component. The disruption of protein homeostasis due to chronic stress responses at the endoplasmic reticulum (ER) and the accumulation of abnormal prote...

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Detalles Bibliográficos
Autores principales: Matus, Soledad, Valenzuela, Vicente, Medinas, Danilo B., Hetz, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845333/
https://www.ncbi.nlm.nih.gov/pubmed/24324498
http://dx.doi.org/10.1155/2013/674751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845333/
https://www.ncbi.nlm.nih.gov/pubmed/24324498
http://dx.doi.org/10.1155/2013/674751

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